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EMD-12553
Paired helical filament from posterior cortical atrophy brain
EMD-12553
Helical reconstruction3.55 Å
Deposition: 04/03/2021Map released: 24/03/2021
Last modified: 28/04/2021
Sample Organism:
Human
Sample: Sarkosyl-insoluble fractions from posterior cortical atrophy brain
Deposition Authors: Shi Y, Murzin AG, Falcon B, Epstein A, Machin J, Tempest P, Newell KL, Vidal R, Garringer HJ, Sahara N, Higuchi M, Ghetti B, Jang M, Scheres SHW, Goedert M
Sample: Sarkosyl-insoluble fractions from posterior cortical atrophy brain
Deposition Authors: Shi Y, Murzin AG, Falcon B, Epstein A, Machin J, Tempest P, Newell KL, Vidal R, Garringer HJ, Sahara N, Higuchi M, Ghetti B, Jang M, Scheres SHW, Goedert M
Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Shi Y,
Murzin AG,
Falcon B,
Epstein A,
Machin J,
Tempest P,
Newell KL,
Vidal R
,
Garringer HJ
,
Sahara N
,
Higuchi M,
Ghetti B,
Jang MK,
Scheres SHW,
Goedert M
(2021) Acta Neuropathol , 141 , 697 - 708
,
Garringer HJ
,
Sahara N
,
Higuchi M,
Ghetti B,
Jang MK,
Scheres SHW,
Goedert M
(2021) Acta Neuropathol , 141 , 697 - 708
Grant Support:
- Medical Research Council (MRC, United Kingdom): MC_UP_A025_1013 (United Kingdom)
- Medical Research Council (MRC, United Kingdom): MC_U105184291 (United Kingdom)
- Innovative Medicines Initiative: 116060 (European Union)
- National Institutes of Health/National Institute on Aging (NIH/NIA): P30-AG010133 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): U01-NS110437 (United States)
- Japan Agency for Medical Research and Development (AMED): JP20dm0207072 (Japan)
