EMD-12549

Helical reconstruction
2.76 Å
EMD-12549
3D View Gallery
Deposition: 04/03/2021
Map released: 24/03/2021
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-12549
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7nrq summary report (pdf.gz) Map and 7nrq FULL report (pdf.gz)
EMICSS annotations (xml)

Paired helical filament from primary age-related tauopathy brain

EMD-12549

Helical reconstruction
2.76 Å
EMD-12549
3D View Gallery
Deposition: 04/03/2021
Map released: 24/03/2021
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Sarkosyl-insoluble fractions from primary age-related tauopathy brain
Fitted models: 7nrq

Deposition Authors: Shi Y, Murzin AG
Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Shi Y, Murzin AG, Falcon B, Epstein A, Machin J, Tempest P, Newell KL, Vidal R , Garringer HJ , Sahara N , Higuchi M, Ghetti B, Jang MK, Scheres SHW, Goedert M
(2021) Acta Neuropathol , 141 , 697 - 708
PUBMED: 33723967
DOI: doi:10.1007/s00401-021-02294-3
ISSN: 1432-0533