EMD-12265

Helical reconstruction
3.43 Å
EMD-12265
3D View Gallery
Deposition: 28/01/2021
Map released: 24/02/2021
Last modified: 01/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-12265
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7ncg summary report (pdf.gz) Map and 7ncg FULL report (pdf.gz)
EMICSS annotations (xml)

Type 2A alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 2

EMD-12265

Helical reconstruction
3.43 Å
EMD-12265
3D View Gallery
Deposition: 28/01/2021
Map released: 24/02/2021
Last modified: 01/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Alpha synuclein filament
Fitted models: 7ncg

Deposition Authors: Lovestam SKA, Schweighauser M
Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy.
Lovestam S , Schweighauser M , Matsubara T , Murayama S, Tomita T, Ando T , Hasegawa K, Yoshida M, Tarutani A , Hasegawa M, Goedert M , Scheres SHW
(2021) FEBS Open Bio , 11 , 999 - 1013
PUBMED: 33548114
DOI: doi:10.1002/2211-5463.13110
ISSN: 2211-5463