EMD-11941

Single-particle
12.0 Å
EMD-11941
3D View Gallery
Deposition: 16/11/2020
Map released: 17/02/2021
Last modified: 17/02/2021
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-11941

Archive Files (Depositor)

Primary 3D volume (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

CryoEM analysis of ternary complex of full-length Caspase-8 with FADD and FLIPs

EMD-11941

Single-particle
12.0 Å
EMD-11941
3D View Gallery
Deposition: 16/11/2020
Map released: 17/02/2021
Last modified: 17/02/2021
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Ternary Complex of Full-length Caspase-8:FADD:FLIPs

Deposition Authors: Fox JL, Ragan TJ, Dinsdale D, Fairall L, Schwabe JWR, Morone N, Cain K, MacFarlane M
Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate.
Fox JL , Hughes MA, Meng X, Sarnowska NA, Powley IR, Jukes-Jones R, Dinsdale D, Ragan TJ , Fairall L , Schwabe JWR , Morone N , Cain K, MacFarlane M
(2021) Nat Commun , 12 , 819 - 819
PUBMED: 33547302
DOI: doi:10.1038/s41467-020-20806-9
ISSN: 2041-1723
Grant Support: