EMDB EMD-11939

Single particle reconstruction
15.0Å resolution

Central region of Caspase-8:FADD ternary complex

Map released:
Overview of EMD-11939
Source organism: Homo sapiens [9606]
Primary publication:
Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate.
Fox JL, Hughes MA, Meng X, Sarnowska NA, Powley IR, Jukes-Jones R, Dinsdale D, Ragan TJ, Fairall L, Schwabe JWR, Morone N, Cain K, MacFarlane M
Nat Commun 12 819-819 (2021)
PMID: 33547302

Function and Biology Details

Sample name: Central region of ternary complex of full-length Caspase-8 with FADD
Protein: Central region of ternary complex of full-length Caspase-8 with FADD

Experimental Information Details

Resolution: 15.0Å
Resolution method: FSC 0.143 CUT-OFF
Reconstruction software: cryoSPARC
Microscope: FEI TALOS ARCTICA
Detector: FEI CETA (4k x 4k)