EMDB EMD-11938

Single particle reconstruction
22.41Å resolution

Ternary complex of full-length Caspase-8 and FADD

Map released:
Overview of EMD-11938
Source organism: Homo sapiens [9606]
Primary publication:
Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate.
Fox JL, Hughes MA, Meng X, Sarnowska NA, Powley IR, Jukes-Jones R, Dinsdale D, Ragan TJ, Fairall L, Schwabe JWR, Morone N, Cain K, MacFarlane M
Nat Commun 12 819-819 (2021)
PMID: 33547302

Function and Biology Details

Sample name: Ternary complex of full-length Caspase-8 with FADD
Protein: Ternary complex of full-length Caspase-8 with FADD

Experimental Information Details

Resolution: 22.41Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: cryoSPARC
Microscope: FEI TALOS ARCTICA
Detector: FEI CETA (4k x 4k)