EMD-11671

Single-particle
3.6 Å
EMD-11671
3D View Gallery
Deposition: 25/08/2020
Map released: 14/10/2020
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-11671

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7a6e summary report (pdf.gz) Map-7a6e FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and tariquidar

EMD-11671

Single-particle
3.6 Å
EMD-11671
3D View Gallery
Deposition: 25/08/2020
Map released: 14/10/2020
Last modified: 09/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Homo sapiens
Sample: Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and tariquidar
Fitted models: 7a6e

Deposition Authors: Nosol K , Locher KP
Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1.
Nosol K , Romane K , Irobalieva RN , Alam A, Kowal J , Fujita N , Locher KP
(2020) PNAS , 117 , 26245 - 26253
PUBMED: 33020312
DOI: doi:10.1073/pnas.2010264117
ISSN: 1091-6490
ASTM: PNASA6
Grant Support: