EMD-11610

Single-particle
3.0 Å
EMD-11610
3D View Gallery
Deposition: 13/08/2020
Map released: 04/08/2021
Last modified: 04/08/2021
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-11610
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CryoEM structure of a beta3K279T GABA(A)R homomer in complex with megabody MbNbF3c7HopQ

EMD-11610

Single-particle
3.0 Å
EMD-11610
3D View Gallery
Deposition: 13/08/2020
Map released: 04/08/2021
Last modified: 04/08/2021
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama
Sample: Homomeric truncated (M3-M4 loop) GABAAR b3K279T receptor in complex with megabody MbNbF3c7HopQ

Deposition Authors: Uchanski T, Masiulis S
Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM.
Uchanski T , Masiulis S, Fischer B , Kalichuk V , Lopez-Sanchez U , Zarkadas E , Weckener M , Sente A , Ward P, Wohlkonig A , Zogg T , Remaut H , Naismith JH, Nury H, Vranken W , Aricescu AR , Pardon E , Steyaert J
(2021) Nat. Methods , 18 , 60 - 68
PUBMED: 33408403
DOI: doi:10.1038/s41592-020-01001-6
ISSN: 1548-7105