EMD-11554

Single-particle
7.4 Å
EMD-11554
3D View Gallery
Deposition: 30/07/2020
Map released: 26/05/2021
Last modified: 01/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-11554

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-6zy8 summary report (pdf.gz) Map-6zy8 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the entire Human topoisomerase II alpha in State 2

EMD-11554

Single-particle
7.4 Å
EMD-11554
3D View Gallery
Deposition: 30/07/2020
Map released: 26/05/2021
Last modified: 01/05/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Etoposide-bound Entire Human Top2a in state 2
Fitted models: 6zy8

Deposition Authors: Vanden Broeck A , Lamour V
Structural basis for allosteric regulation of Human Topoisomerase II alpha.
Vanden Broeck A , Lotz C , Drillien R, Haas L , Bedez C, Lamour V
(2021) Nat Commun , 12 , 2962 - 2962
PUBMED: 34016969
DOI: doi:10.1038/s41467-021-23136-6
ISSN: 2041-1723