EMDB EMD-11492

Single particle reconstruction
3.0Å resolution

cryo-EM structure of human mTOR complex 2, focused on one half

Map released:
Overview of EMD-11492
Source organism: Homo sapiens [9606]
Fitted atomic model: 6zwo
Related EM entries by publication: EMD-11488, EMD-11489, EMD-11490, EMD-11491
Primary publication:
The 3.2- angstrom resolution structure of human mTORC2.
Scaiola A, Mangia F, Imseng S, Boehringer D, Berneiser K, Shimobayashi M, Stuttfeld E, Hall MN, Ban N, Maier T
Sci Adv 6 - (2020)
PMID: 33158864

Function and Biology Details

Sample name: human mTOR complex 2
Ligands: PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, INOSITOL HEXAKISPHOSPHATE, ZINC ION, ACETYL GROUP
Proteins: human mTOR complex 2, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8, Rapamycin-insensitive companion of mTOR, Target of rapamycin complex 2 subunit MAPKAP1

Experimental Information Details

Resolution: 3.0Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)