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EMD-11467

Single-particle
4.0 Å
EMD-11467
3D View Gallery
Deposition: 27/07/2020
Map released: 17/11/2021
Last modified: 02/02/2022
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-11467
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6zvp summary report (pdf.gz) Map and 6zvp FULL report (pdf.gz)
EMICSS annotations (xml)

Atomic model of the EM-based structure of the full-length tyrosine hydroxylase in complex with dopamine (residues 40-497) in which the regulatory domain (residues 40-165) has been included only with the backbone atoms

EMD-11467

Single-particle
4.0 Å
EMD-11467
3D View Gallery
Deposition: 27/07/2020
Map released: 17/11/2021
Last modified: 02/02/2022
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: Tyrosine Hydroxylase in complex with dopamine
Fitted models: 6zvp

Deposition Authors: Bueno-Carrasco MT , Cuellar J , Santiago C , Valpuesta JM , Martinez A , Flydal MI
Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation.
Bueno-Carrasco MT , Cuellar J , Flydal MI , Santiago C , Krakenes TA , Kleppe R, Lopez-Blanco JR , Marcilla M , Teigen K , Alvira S , Chacon P , Martinez A , Valpuesta JM
(2022) Nat Commun , 13 , 74 - 74
PUBMED: 35013193
DOI: doi:10.1038/s41467-021-27657-y
ISSN: 2041-1723