EMDB EMD-11187

Single particle reconstruction
2.88Å resolution

hSARM1 GraFix-ed

Map released:
Last modified:
Overview of EMD-11187
Source organism: Homo sapiens [9606]
Fitted atomic model: 6zfx
Related EM entries by publication: EMD-11190, EMD-11191, EMD-11834
Primary publication:
The structural basis for SARM1 inhibition and activation under energetic stress.
Sporny M, Guez-Haddad J, Khazma T, Yaron A, Dessau M, Shkolnisky Y, Mim C, Isupov MN, Zalk R, Hons M, Opatowsky Y
Elife 9 - (2020)
PMID: 33185189

Function and Biology Details

Sample name: hSARM1
Ligand: (~{E})-4-methylnon-4-enedial
Proteins: hSARM1, NAD(+) hydrolase SARM1

Experimental Information Details

Resolution: 2.88Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)