EMDB EMD-10774

Single particle reconstruction
3.8Å resolution

Structure of a human 48S translational initiation complex - eIF2-TC

Map released:
Overview of EMD-10774
Source organism: Human [9606]
Fitted atomic model: 6ybv
Related EM entries by publication: EMD-10769, EMD-10772, EMD-10773, EMD-10775, EMD-11302
Primary publication:
Structure of a human 48Stranslational initiation complex.
Brito Querido J, Sokabe M, Kraatz S, Gordiyenko Y, Skehel JM, Fraser CS, Ramakrishnan V
Science 369 1220-1227 (2020)
PMID: 32883864

Function and Biology Details

Sample name: 48S initiation complex
Nucleic acids: Initiator methionine tRNA, mRNA
Proteins: 48S initiation complex, Eukaryotic translation initiation factor 2 subunit 2, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3

Experimental Information Details

Resolution: 3.8Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: FEI FALCON III (4k x 4k)