EMDB EMD-10772

Single particle reconstruction
3.1Å resolution

Structure of a human 48S translational initiation complex - head

Map released:
Overview of EMD-10772
Source organism: Human [9606]
Fitted atomic model: 6ybs
Related EM entries by publication: EMD-10769, EMD-10773, EMD-10774, EMD-10775, EMD-11302
Primary publication:
Structure of a human 48Stranslational initiation complex.
Brito Querido J, Sokabe M, Kraatz S, Gordiyenko Y, Skehel JM, Fraser CS, Ramakrishnan V
Science 369 1220-1227 (2020)
PMID: 32883864

Function and Biology Details

Sample name: 48S initiation complex
Ligands: MAGNESIUM ION, ZINC ION
Nucleic acid: 18S rRNA
Proteins: 48S initiation complex, Eukaryotic translation initiation factor 3 subunit D, Receptor of activated protein C kinase 1, 40S ribosomal protein S28, 40S ribosomal protein S17, 40S ribosomal protein S20, Eukaryotic translation initiation factor 3 subunit G, 40S ribosomal protein S10, 40S ribosomal protein S12, 40S ribosomal protein S29, 40S ribosomal protein S15, 40S ribosomal protein S3, 40S ribosomal protein S19, 40S ribosomal protein S25, 40S ribosomal protein S18, 40S ribosomal protein S5, Ubiquitin-40S ribosomal protein S27a, 40S ribosomal protein S16

Experimental Information Details

Resolution: 3.1Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: FEI FALCON III (4k x 4k)