EMDB EMD-10769

Single particle reconstruction
3.3Å resolution

Structure of a human 48S translational initiation complex - eIF3

Map released:
Overview of EMD-10769
Source organism: Human [9606]
Fitted atomic model: 6ybd
Related EM entries by publication: EMD-10772, EMD-10773, EMD-10774, EMD-10775, EMD-11302
Primary publication:
Structure of a human 48Stranslational initiation complex.
Brito Querido J, Sokabe M, Kraatz S, Gordiyenko Y, Skehel JM, Fraser CS, Ramakrishnan V
Science 369 1220-1227 (2020)
PMID: 32883864

Function and Biology Details

Sample name: 48S initiation complex
Proteins: 48S initiation complex, Eukaryotic translation initiation factor 3 subunit M, Eukaryotic translation initiation factor 3 subunit F, Eukaryotic translation initiation factor 3 subunit A, Eukaryotic translation initiation factor 3 subunit E, Eukaryotic translation initiation factor 3 subunit C, Eukaryotic translation initiation factor 3 subunit H, 40S ribosomal protein S7, 40S ribosomal protein S27, 40S ribosomal protein S21, 40S ribosomal protein S17, 40S ribosomal protein S2, 40S ribosomal protein S3a, 40S ribosomal protein SA, 40S ribosomal protein S26, 40S ribosomal protein S14, 40S ribosomal protein S13, Eukaryotic translation initiation factor 3 subunit D, Eukaryotic translation initiation factor 3 subunit K, Eukaryotic translation initiation factor 3 subunit L

Experimental Information Details

Resolution: 3.3Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: FEI FALCON III (4k x 4k)