Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-10709
Tetracenomycin X bound to the human ribosome
EMD-10709
Single-particle2.8 Å
Deposition: 27/02/2020Map released: 08/07/2020
Last modified: 08/11/2023
Sample Organism:
Homo sapiens
Sample: Tetracenomycin bound to the human ribosome
Fitted models: 6y6x
Deposition Authors: Buschauer R
,
Cheng J
Sample: Tetracenomycin bound to the human ribosome
Fitted models: 6y6x
Deposition Authors: Buschauer R
,
Cheng J
Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
Osterman IA ,
Wieland M ,
Maviza TP ,
Lashkevich KA ,
Lukianov DA ,
Komarova ES ,
Zakalyukina YV ,
Buschauer R ,
Shiriaev DI ,
Leyn SA ,
Zlamal JE,
Biryukov MV ,
Skvortsov DA,
Tashlitsky VN ,
Polshakov VI ,
Cheng J ,
Polikanov YS ,
Bogdanov AA,
Osterman AL,
Dmitriev SE ,
Beckmann R,
Dontsova OA,
Wilson DN ,
Sergiev PV
(2020) Nat Chem Biol , 16 , 1071 - 1077
,
Wieland M ,
Maviza TP ,
Lashkevich KA ,
Lukianov DA ,
Komarova ES ,
Zakalyukina YV ,
Buschauer R ,
Shiriaev DI ,
Leyn SA ,
Zlamal JE,
Biryukov MV ,
Skvortsov DA,
Tashlitsky VN ,
Polshakov VI ,
Cheng J ,
Polikanov YS ,
Bogdanov AA,
Osterman AL,
Dmitriev SE ,
Beckmann R,
Dontsova OA,
Wilson DN ,
Sergiev PV
(2020) Nat Chem Biol , 16 , 1071 - 1077