EMD-10655

Single-particle
2.1 Å
EMD-10655
3D View Gallery
Deposition: 03/02/2020
Map released: 22/07/2020
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-10655
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6xz7 summary report (pdf.gz) Map and 6xz7 FULL report (pdf.gz)
EMICSS annotations (xml)

E. coli 50S ribosomal subunit in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet).

EMD-10655

Single-particle
2.1 Å
EMD-10655
3D View Gallery
Deposition: 03/02/2020
Map released: 22/07/2020
Last modified: 12/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli (strain K12), Saccharomyces cerevisiae
Sample: E. coli 50S ribosomal subunit in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet).
Fitted models: 6xz7

Deposition Authors: Pichkur EB, Polikanov YS
Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to theE. coli70S ribosome.
Pichkur EB, Paleskava A, Tereshchenkov AG , Kasatsky P, Komarova ES, Shiriaev DI, Bogdanov AA, Dontsova OA, Osterman IA, Sergiev PV, Polikanov YS , Myasnikov AG, Konevega AL
(2020) RNA , 26 , 715 - 723
PUBMED: 32144191
DOI: doi:10.1261/rna.073817.119
ISSN: 1469-9001
ASTM: RNARFU