Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-10583

Single-particle
6.7 Å
EMD-10583
3D View Gallery
Deposition: 27/12/2019
Map released: 19/02/2020
Last modified: 04/03/2020
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-10583
Download
3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
EMICSS annotations (xml)

Dynamic neddylated Cullin-RING E3 ligase: NEDD8-CUL1-RBX1-SKP1-b-TRCP1dD-IkBa

EMD-10583

Single-particle
6.7 Å
EMD-10583
3D View Gallery
Deposition: 27/12/2019
Map released: 19/02/2020
Last modified: 04/03/2020
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Dynamic neddylated Cullin-RING E3 ligase: NEDD8-CUL1-RBX1-SKP1-b-TRCP1dD-IkBa

Deposition Authors: Baek K, Prabu JR, Schulman BA
NEDD8 nucleates a multivalent cullin-RING-UBE2D ubiquitin ligation assembly.
Baek K, Krist DT, Prabu JR, Hill S, Klugel M, Neumaier LM, von Gronau S, Kleiger G, Schulman BA
(2020) Nature , 578 , 461 - 466
PUBMED: 32051583
DOI: doi:10.1038/s41586-020-2000-y
ISSN: 1476-4687
ASTM: NATUAS
Grant Support: