EMDB EMD-10563

Single particle reconstruction
2.3Å resolution

Beta-galactosidase in complex with deoxygalacto-nojirimycin

Map released:
Last modified:
Overview of EMD-10563
Source organism: Escherichia coli [562]
Fitted atomic model: 6tsh
Related EM entries by publication: EMD-10564, EMD-10574, EMD-10575, EMD-10576, EMD-10577, EMD-10584
Primary publication:
Fragment-based drug discovery using cryo-EM.
Saur M, Hartshorn MJ, Dong J, Reeks J, Bunkoczi G, Jhoti H, Williams PA
Drug Discov Today - (2019)
PMID: 31877353

Function and Biology Details

Sample name: Beta-galactosidase
Ligands: MAGNESIUM ION, (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, water
Proteins: Beta-galactosidase, Beta-galactosidase

Experimental Information Details

Resolution: 2.3Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: D2
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: FEI FALCON III (4k x 4k)