EMDB EMD-10290

Single particle reconstruction
4.2Å resolution

Structure of Fanconi anaemia core complex (consensus map)

Map released:
Last modified:
Overview of EMD-10290
Source organism: Gallus gallus [9031]
Fitted atomic model: 6sri
Related EM entries by publication: EMD-10291, EMD-10292, EMD-10293, EMD-10294
Primary publication:
Structure of the Fanconi anaemia monoubiquitin ligase complex.
Shakeel S, Rajendra E, Alcon P, O'Reilly F, Chorev DS, Maslen S, Degliesposti G, Russo CJ, He S, Hill CH, Skehel JM, Scheres SHW, Patel KJ, Rappsilber J, Robinson CV, Passmore LA
Nature 575 234-237 (2019)
PMID: 31666700

Function and Biology Details

Sample name: Fanconi anaemia core complex
Proteins: Fanconi anaemia core complex, Unassigned secondary structure elements (central region, proposed FANCB-FAAP100: chain A,a; base region, proposed FANCC-FANC-E-FANCF: chain 3), Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), Unassigned secondary structure elements (central region, proposed FANCB-FAAP100: chain F,f; base region, proposed FANCC-FANC-E-FANCF: chain Z), Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), Unassigned secondary structure elements (proposed FANCB), Unassigned secondary structure elements (proposed FAAP100), Unassigned secondary structure elements (proposed FANCB), Unassigned secondary structure elements (proposed FAAP100), Unassigned secondary structure elements (base region, proposed FANCC-FANC-E-FANCF), Unassigned secondary structure elements (base region, proposed FANCC-FANC-E-FANCF), Unassigned secondary structure elements (base region, proposed FANCC-FANC-E-FANCF), Unassigned secondary structure elements (base region, proposed FANCC-FANC-E-FANCF), Unassigned secondary structure elements (base region, proposed FANCC-FANC-E-FANCF), Unassigned secondary structure elements (base region, proposed FANCC-FANC-E-FANCF), Unassigned secondary structure elements (base region, proposed FANCC-FANC-E-FANCF), Unassigned secondary structure elements (base region, proposed FANCC-FANC-E-FANCF), Fanconi anaemia protein FANCL, base region, proposed FANCF, Unassigned secondary structure elements (top region, proposed FANCG), Unassigned secondary structure elements (top region, proposed FANCG)

Experimental Information Details

Resolution: 4.2Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: FEI FALCON III (4k x 4k)