EMDB EMD-10152

Single particle reconstruction
3.5Å resolution

Class2 : CENP-A nucleosome in complex with CENP-C central region

Map released:
Last modified:
Overview of EMD-10152
Source organisms:
Fitted atomic model: 6se6
Primary publication:
CENP-C unwraps the human CENP-A nucleosome through the H2A C-terminal tail.
Ali-Ahmad A, Bilokapic S, Schafer IB, Halic M, Sekulic N
Embo Rep. e48913-e48913 (2019)
PMID: 31475439

Function and Biology Details

Sample name: CENP-A nucleosome
Nucleic acids: DNA (145-MER), DNA (145-MER)
Proteins: CENP-A nucleosome, Histones, DNA, Histone H3-like centromeric protein A, Histone H4, Histone H2A type 2-A, Histone H2B type 1-C/E/F/G/I, Centromere protein C

Experimental Information Details

Resolution: 3.5Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)