EMDB EMD-10072

Single particle reconstruction
6.6Å resolution

cryo EM map of human APC/CCDH1 bound to the avid UbVW_dim trap

Map released:
Overview of EMD-10072
Source organism: Homo sapiens [9606]
Primary publication:
Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site.
Watson ER, Grace CRR, Zhang W, Miller DJ, Davidson IF, Prabu JR, Yu S, Bolhuis DL, Kulko ET, Vollrath R, Haselbach D, Stark H, Peters JM, Brown NG, Sidhu SS, Schulman BA
Proc.Natl.Acad.Sci.USA - (2019)
PMID: 31350353

Function and Biology Details

Sample name: Anaphase-Promoting Complex/Cyclosome
Protein: Anaphase-Promoting Complex/Cyclosome

Experimental Information Details

Resolution: 6.6Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)