EMDB EMD-10018

Single particle reconstruction
4.13Å resolution

Inward-open structure of the ASCT2 (SLC1A5) mutant C467R in absence of substrate

Map released:
Last modified:
Overview of EMD-10018
Source organism: Homo sapiens [9606]
Fitted atomic model: 6rvy
Related EM entry by publication: EMD-10016, EMD-10017
Primary publication:
A one-gate elevator mechanism for the human neutral amino acid transporter ASCT2.
Garaeva AA, Guskov A, Slotboom DJ, Paulino C
Nat Commun 10 3427-3427 (2019)
PMID: 31366933

Function and Biology Details

Sample name: C467R mutant of ASCT2 (Alanine Serine Cysteine Transporter 2, SLC1A)
Proteins: C467R mutant of ASCT2 (Alanine Serine Cysteine Transporter 2, SLC1A), Neutral amino acid transporter B(0)

Experimental Information Details

Resolution: 4.13Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C3
Reconstruction software: RELION
Microscope: FEI TALOS ARCTICA
Detector: GATAN K2 SUMMIT (4k x 4k)