EMDB EMD-10016

Single particle reconstruction
3.61Å resolution

Inward-open structure of the ASCT2 (SLC1A5) mutant C467R in presence of TBOA

Map released:
Last modified:
Overview of EMD-10016
Source organism: Homo sapiens [9606]
Fitted atomic model: 6rvx
Related EM entry by publication: EMD-10017, EMD-10018
Primary publication:
A one-gate elevator mechanism for the human neutral amino acid transporter ASCT2.
Garaeva AA, Guskov A, Slotboom DJ, Paulino C
Nat Commun 10 3427-3427 (2019)
PMID: 31366933

Function and Biology Details

Sample name: C467R mutant of ASCT2 (Alanine Serine Cysteine Transporter 2, SLC1A)
Proteins: C467R mutant of ASCT2 (Alanine Serine Cysteine Transporter 2, SLC1A), Neutral amino acid transporter B(0)

Experimental Information Details

Resolution: 3.61Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C3
Reconstruction software: RELION
Microscope: FEI TALOS ARCTICA
Detector: GATAN K2 SUMMIT (4k x 4k)