EMDB EMD-0882

Single particle reconstruction
3.4Å resolution

cryo-EM structure of TRPV3 in lipid nanodisc

Map released:
Last modified:
Overview of EMD-0882
Source organism: Mus musculus [10090]
Fitted atomic model: 6lgp
Primary publication:
The structure of lipid nanodisc-reconstituted TRPV3 reveals the gating mechanism.
Shimada H, Kusakizako T, Dung Nguyen TH, Nishizawa T, Hino T, Tominaga M, Nureki O
Nat.Struct.Mol.Biol. - (2020)
PMID: 32572254

Function and Biology Details

Sample name: TRPV3
Cellular component: TRPV3
Ligands: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, DIUNDECYL PHOSPHATIDYL CHOLINE
Protein: Transient receptor potential cation channel subfamily V member 3

Experimental Information Details

Resolution: 3.4Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C4
Microscope: FEI TITAN KRIOS
Detector: FEI FALCON III (4k x 4k)