EMDB EMD-0741

Single particle reconstruction
7.7Å resolution

cryoEM 3D reconstruction of IGF1R in complex with IGF1

Map released:
Overview of EMD-0741
Source organism: Homo sapiens [9606]
Related EM entry by publication: EMD-9838
Primary publication:
Visualization of Ligand-Bound Ectodomain Assembly in the Full-Length Human IGF-1 Receptor by Cryo-EM Single-Particle Analysis.
Zhang X, Yu D, Sun J, Wu Y, Gong J, Li X, Liu L, Liu S, Liu J, Wu Y, Li D, Ma Y, Han X, Zhu Y, Wu Z, Wang Y, Ouyang Q, Wang T
Structure 28 555-561.e4 (2020)
PMID: 32275863

Function and Biology Details

Sample name: IGF1R
Proteins: IGF1R, IGF1 receptor

Experimental Information Details

Resolution: 7.7Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)