EMDB EMD-0631

Single particle reconstruction
3.6Å resolution

Structure of the TRPM8 cold receptor by single particle electron cryo-microscopy, ligand-free state

Map released:
Last modified:
Overview of EMD-0631
Source organism: Parus major [9157]
Fitted atomic model: 6o6a
Related EM entries by publication: EMD-0636, EMD-0638, EMD-0639
Primary publication:
Structural insights into TRPM8 inhibition and desensitization.
Diver MM, Cheng Y, Julius D
Science - (2019)
PMID: 31488702

Function and Biology Details

Sample name: Transient receptor potential cation channel subfamily M member 8
Ligands: CHOLESTEROL HEMISUCCINATE, SODIUM ION
Proteins: Transient receptor potential cation channel subfamily M member 8, Transient receptor potential cation channel subfamily M member 8

Experimental Information Details

Resolution: 3.6Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C4
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)