EMD-0568

Single-particle
4.11 Å
EMD-0568
3D View Gallery
Deposition: 16/02/2019
Map released: 01/05/2019
Last modified: 08/05/2019
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-0568
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Cryo-EM 3D map of human ATP-citrate lyase N-terminal segment in complex with inhibitor NDI-091143

EMD-0568

Single-particle
4.11 Å
EMD-0568
3D View Gallery
Deposition: 16/02/2019
Map released: 01/05/2019
Last modified: 08/05/2019
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: protein-inhibitor complex

Deposition Authors: Wei J, Tong L
An allosteric mechanism for potent inhibition of human ATP-citrate lyase.
Wei J, Leit S, Kuai J, Therrien E , Rafi S, Harwood Jr HJ, DeLaBarre B, Tong L
(2019) Nature , 568 , 566 - 570
PUBMED: 30944472
DOI: doi:10.1038/s41586-019-1094-6
ISSN: 1476-4687
ASTM: NATUAS