EMDB EMD-0557

Single particle reconstruction
2.8Å resolution

Structural basis for human coronavirus attachment to sialic acid receptors

Map released:
Last modified:
Overview of EMD-0557
Source organisms:
Fitted atomic model: 6nzk
Related EM entry by publication: EMD-20070
Primary publication:
Structural basis for human coronavirus attachment to sialic acid receptors.
Alejandra Tortorici M, Walls AC, Lang Y, Wang C, Li Z, Koerhuis D, Boons GJ, Bosch BJ, Rey FA, de Groot RJ, Veesler D
Nat.Struct.Mol.Biol. 26 481-489 (2019)
PMID: 31160783

Function and Biology Details

Sample name: HCoV-OC43 spike glycoprotein ectodomain in complex with 9-O-acetyl sialic acid
Ligands: N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ALPHA-D-MANNOSE, methyl 9-O-acetyl-5-(acetylamino)-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosidonic acid, water
Proteins: HCoV-OC43 spike glycoprotein ectodomain in complex with 9-O-acetyl sialic acid, Spike surface glycoprotein

Experimental Information Details

Resolution: 2.8Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C3
Reconstruction software: cryoSPARC
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)