Single particle reconstruction
2.4Å resolution

Cryo-EM structure of AAV-2 in complex with AAVR PKD domains 1 and 2

Map released:
Last modified:
Overview of EMD-0553
Source organisms:
Fitted atomic model: 6nz0
Related EM entries by publication: EMD-0621, EMD-0622, EMD-0623, EMD-0624
Primary publication:
Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR.
Meyer NL, Hu G, Davulcu O, Xie Q, Noble AJ, Yoshioka C, Gingerich DS, Trzynka A, David L, Stagg SM, Chapman MS
Elife 8 - (2019)
PMID: 31115336

Function and Biology Details

Sample name: Adeno-associated virus - 2
Ligands: MAGNESIUM ION, water
Proteins: Binary complex of AAV-2 with a fragment of its cellular receptor, AAVR or dyslexia-associated protein KIAA0319-like protein., Dyslexia-associated protein KIAA0319-like protein, Capsid protein VP1
Virus: Adeno-associated virus - 2

Experimental Information Details

Resolution: 2.4Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: I
Reconstruction software: RELION
Detector: FEI FALCON III (4k x 4k)