EMDB EMD-0526

Single particle reconstruction
3.5Å resolution

Structure of drug-like molecule stalled USO1 ribosome nascent chain complex (human)

Map released:
Last modified:
Overview of EMD-0526
Source organism: Homo sapiens [9606]
Fitted atomic model: 6oli
Primary publication:
Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Li W, Ward FR, McClure KF, Chang ST, Montabana E, Liras S, Dullea RG, Cate JHD
Nat.Struct.Mol.Biol. 26 501-509 (2019)
PMID: 31160784

Function and Biology Details

Sample name: Drug-like molecule PF846 stalled human ribosome nascent chain complex, USO1-RNC
Nucleic acid: Drug-like molecule PF846 stalled human ribosome nascent chain complex, USO1-RNC
Protein: Drug-like molecule PF846 stalled human ribosome nascent chain complex, USO1-RNC

Experimental Information Details

Resolution: 3.5Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)