EMDB EMD-0478

Single particle reconstruction
3.5Å resolution

Cryo-EM structure of human TPC2 channel in the apo state

Map released:
Overview of EMD-0478
Source organism: Homo sapiens [9606]
Fitted atomic model: 6nq1
Related EM entry by publication: EMD-0477, EMD-0479
Primary publication:
Structural mechanisms of phospholipid activation of the human TPC2 channel.
She J, Zeng W, Guo J, Chen Q, Bai X, Jiang Y
Elife 8 - (2019)
PMID: 30860481

Function and Biology Details

Sample name: Two-pore channel 2
Proteins: Two-pore channel 2, Two pore calcium channel protein 2

Experimental Information Details

Resolution: 3.5Å
Resolution method: FSC 0.143 CUT-OFF
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)