Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-0437

Single-particle
4.8 Å
EMD-0437 Deposition: 11/12/2018
Map released: 24/04/2019
Last modified: 11/12/2019
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-0437

Cryo-EM structure of the wild-type human serotonin transporter in complex with 15B8 Fab bound to noribogaine

EMD-0437

Single-particle
4.8 Å
EMD-0437 Deposition: 11/12/2018
Map released: 24/04/2019
Last modified: 11/12/2019
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Human serotonin transporter in complex with Fab bound to noribogaine

Deposition Authors: Yang D, Coleman JA, Gouaux E
Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport.
Coleman JA, Yang D, Zhao Z , Wen PC , Yoshioka C, Tajkhorshid E, Gouaux E
(2019) Nature , 569 , 141 - 145
PUBMED: 31019304
DOI: doi:10.1038/s41586-019-1135-1
ISSN: 1476-4687
ASTM: NATUAS