EMDB EMD-0405

Electron crystallography

Amyloid-Beta (20-34) with L-isoaspartate 23

Map released:
Overview of EMD-0405
Source organism: Homo sapiens [9606]
Fitted atomic model: 6nb9
Related EM entry by publication: EMD-20082
Primary publication:
Structure of amyloid-beta (20-34) with Alzheimer's-associated isomerization at Asp23 reveals a distinct protofilament interface.
Warmack RA, Boyer DR, Zee CT, Richards LS, Sawaya MR, Cascio D, Gonen T, Eisenberg DS, Clarke SG
Nat Commun 10 3357-3357 (2019)
PMID: 31350392

Function and Biology Details

Sample name: crystal of amyloid-beta residues 20-34 with L-isoaspartate at position 23
Ligand: water
Proteins: crystal of amyloid-beta residues 20-34 with L-isoaspartate at position 23, Amyloid-beta A4 protein

Experimental Information Details

Resolution method: DIFFRACTION PATTERN/LAYERLINES
Microscope: FEI TALOS ARCTICA
Detector: FEI CETA (4k x 4k)