EMDB EMD-0402

Single particle reconstruction
3.6Å resolution

MERS-CoV S complex with human neutralizing LCA60 antibody Fab fragment (state 2)

Map released:
Last modified:
Overview of EMD-0402
Fitted atomic model: 6nb4
Related EM entries by publication: EMD-0401, EMD-0403, EMD-0404
Primary publication:
Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Walls AC, Xiong X, Park YJ, Tortorici MA, Snijder J, Quispe J, Cameroni E, Gopal R, Dai M, Lanzavecchia A, Zambon M, Rey FA, Corti D, Veesler D
Cell 176 1026-1039.e15 (2019)
PMID: 30712865

Function and Biology Details

Sample name: MERS-CoV complex with human neutralizing LCA60 antibody Fab fragment (state 2)
Ligands: N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ALPHA-D-MANNOSE
Proteins: MERS-CoV complex with human neutralizing LCA60 antibody Fab fragment (state 2), Spike glycoprotein, LCA60 heavy chain, LCA60 light chain

Experimental Information Details

Resolution: 3.6Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)