EMDB EMD-0401

Single particle reconstruction
3.5Å resolution

MERS-CoV complex with human neutralizing LCA60 antibody Fab fragment (state 1)

Map released:
Overview of EMD-0401
Fitted atomic model: 6nb3
Primary publication:
Unexpected receptor functional mimicry elucidates activation of coronavirus fusion
Walls AC, Xiong X, Park YJ, Tortorici MA, Snijder S, Quispe J, Cameroni E, Gopal R, Mian D, Lanzavecchia A, Zambon M, Rey FA, Corti D, Veesler D
Cell(Cambridge,Mass.) - (2019)

Function and Biology Details

Sample name: MERS-CoV complex with human neutralizing LCA60 antibody Fab fragment (state 1)
Ligands: N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ALPHA-D-MANNOSE
Proteins: MERS-CoV complex with human neutralizing LCA60 antibody Fab fragment (state 1), Spike glycoprotein, LCA60 light chain, LCA60 heavy chain

Experimental Information Details

Resolution: 3.5Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C3
Microscope: FEI TITAN KRIOS
Detector: GATAN K2 SUMMIT (4k x 4k)