EMDB EMD-0111

Single particle reconstruction
4.7Å resolution

Asymmetric region of the Membrane Attack Complex in the open conformation

Map released:
Last modified:
Overview of EMD-0111
Source organism: Homo sapiens [9606]
Related EM entries by publication: EMD-0106, EMD-0107, EMD-0109, EMD-0110, EMD-0112, EMD-0113
Primary publication:
CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Menny A, Serna M, Boyd CM, Gardner S, Joseph AP, Morgan BP, Topf M, Brooks NJ, Bubeck D
Nat Commun 9 5316-5316 (2018)
PMID: 30552328

Function and Biology Details

Sample name: Membrane Attack Complex
Proteins: Membrane Attack Complex, C5b, C6, C7, C8 alpha, C8 beta, C8 gamma, C9

Experimental Information Details

Resolution: 4.7Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: FEI FALCON II (4k x 4k)