EMDB EMD-0107

Single particle reconstruction
5.6Å resolution

Closed conformation of the Membrane Attack Complex

Map released:
Last modified:
Overview of EMD-0107
Source organism: Human [9606]
Fitted atomic model: 6h04
Related EM entries by publication: EMD-0106, EMD-0109, EMD-0110, EMD-0111, EMD-0112, EMD-0113
Primary publication:
CryoEM reveals how the complement membrane attack complex ruptures lipid bilayers.
Menny A, Serna M, Boyd CM, Gardner S, Joseph AP, Morgan BP, Topf M, Brooks NJ, Bubeck D
Nat Commun 9 5316-5316 (2018)
PMID: 30552328

Function and Biology Details

Sample name: Membrane Attack Complex
Ligand: N-ACETYL-D-GLUCOSAMINE
Proteins: Membrane Attack Complex, C5b, C6, C7, C8 alpha, C8 beta, C8 gamma, C9, Complement component C9, Complement C5,Complement C5, Complement component C8 beta chain, Complement component C7, Complement component C8 gamma chain, Complement component C8 alpha chain, Complement component C6

Experimental Information Details

Resolution: 5.6Å
Resolution method: FSC 0.143 CUT-OFF
Applied symmetry: C1
Reconstruction software: RELION
Microscope: FEI TITAN KRIOS
Detector: FEI FALCON II (4k x 4k)