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EMD-54805
Mouse otoferlin (216-1931) in complex with a lipid nanodisc (comprising 25% PS and 5% PIP2)
EMD-54805
Single-particle2.23 Å
Deposition: 15/08/2025Map released: 05/11/2025
Last modified: 05/11/2025
Sample Organism:
Mus musculus
Sample: Mouse otoferlin (216-1931) complexed with an MSP2N2 lipid nanodisc, comprising 25% PS and 5% PIP2
Fitted models: 9sea
Deposition Authors: Cretu C
,
Moser T
Sample: Mouse otoferlin (216-1931) complexed with an MSP2N2 lipid nanodisc, comprising 25% PS and 5% PIP2
Fitted models: 9sea
Deposition Authors: Cretu C
,
Moser T
Structure and function of otoferlin, a synaptic protein of sensory hair cells essential for hearing.
Chen H ,
Cretu C ,
Trebilcock A ,
Evdokimova N ,
Babai N,
Feldmann L,
Leidner F,
Benseler F ,
Mutschall S ,
Esch K ,
Szabo CZK,
Pena V ,
Pape C ,
Grubmuller H ,
Strenzke N ,
Brose N ,
Wichmann C ,
Preobraschenski J ,
Moser T
(2025) Sci Adv , 11 , eady8532 - eady8532
,
Cretu C ,
Trebilcock A ,
Evdokimova N ,
Babai N,
Feldmann L,
Leidner F,
Benseler F ,
Mutschall S ,
Esch K ,
Szabo CZK,
Pena V ,
Pape C ,
Grubmuller H ,
Strenzke N ,
Brose N ,
Wichmann C ,
Preobraschenski J ,
Moser T
(2025) Sci Adv , 11 , eady8532 - eady8532
Grant Support:
- German Research Foundation (DFG): CR 937/2-1 (Germany)