EMD-53945

Single-particle
3.7 Å
EMD-53945
3D View Gallery
Deposition: 05/06/2025
Map released: 14/01/2026
Last modified: 04/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53945
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
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EMICSS annotations (xml)

Co-chaperone Bag1-bound human 26S proteasome in SBag2 state

EMD-53945

Single-particle
3.7 Å
EMD-53945
3D View Gallery
Deposition: 05/06/2025
Map released: 14/01/2026
Last modified: 04/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Co-chaperone Bag1-bound human 26S proteasome in SBag2 state

Deposition Authors: Cheng TC, Sakata E, Muntaner J, Maestro-Lopez M, Cuellar J, Valpuesta JM
Structures of the 26 S proteasome in complex with the Hsp70 co-chaperone Bag1 reveal a mechanism for direct substrate transfer.
Maestro-Lopez M, Cheng TC, Muntaner J, Menendez M, Alonso M, Schweitzer A, Ishizaka M, Tomko Jr RJ, Cuellar J, Valpuesta JM, Sakata E
(2026) Sci Adv , 12 , eadz3026 - eadz3026
PUBMED: 41719407
DOI: doi:10.1126/sciadv.adz3026
ISSN: 2375-2548