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EMD-53046
Mouse otoferlin (216-1931) in complex with an MSP2N2 lipid nanodisc (30 mol% DOPS, 10 mol% PI(4,5)P2)
EMD-53046
Single-particle2.3 Å
Deposition: 07/03/2025Map released: 12/11/2025
Last modified: 12/11/2025
Sample Organism:
Mus musculus
Sample: Mouse otoferlin (residues 216-1931) in complex with an MSP2N2 lipid nanodisc (comprising 30 mol% DOPS and 10 mol% PI(4,5)P2)
Fitted models: 9qe2
Deposition Authors: Cretu C
,
Moser T
Sample: Mouse otoferlin (residues 216-1931) in complex with an MSP2N2 lipid nanodisc (comprising 30 mol% DOPS and 10 mol% PI(4,5)P2)
Fitted models: 9qe2
Deposition Authors: Cretu C
,
Moser T
Structure and function of otoferlin, a synaptic protein of sensory hair cells essential for hearing.
Chen H ,
Cretu C ,
Trebilcock A ,
Evdokimova N ,
Babai N,
Feldmann L,
Leidner F,
Benseler F ,
Mutschall S ,
Esch K ,
Szabo CZK,
Pena V ,
Pape C ,
Grubmuller H ,
Strenzke N ,
Brose N ,
Wichmann C ,
Preobraschenski J ,
Moser T
(2025) Sci Adv , 11 , eady8532 - eady8532
,
Cretu C ,
Trebilcock A ,
Evdokimova N ,
Babai N,
Feldmann L,
Leidner F,
Benseler F ,
Mutschall S ,
Esch K ,
Szabo CZK,
Pena V ,
Pape C ,
Grubmuller H ,
Strenzke N ,
Brose N ,
Wichmann C ,
Preobraschenski J ,
Moser T
(2025) Sci Adv , 11 , eady8532 - eady8532
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