EMD-53046

Single-particle
2.3 Å
EMD-53046
3D View Gallery
Deposition: 07/03/2025
Map released: 12/11/2025
Last modified: 12/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-53046

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9qe2 summary report (pdf.gz) Map-9qe2 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Mouse otoferlin (216-1931) in complex with an MSP2N2 lipid nanodisc (30 mol% DOPS, 10 mol% PI(4,5)P2)

EMD-53046

Single-particle
2.3 Å
EMD-53046
3D View Gallery
Deposition: 07/03/2025
Map released: 12/11/2025
Last modified: 12/11/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Mouse otoferlin (residues 216-1931) in complex with an MSP2N2 lipid nanodisc (comprising 30 mol% DOPS and 10 mol% PI(4,5)P2)
Fitted models: 9qe2

Deposition Authors: Cretu C , Moser T
Structure and function of otoferlin, a synaptic protein of sensory hair cells essential for hearing.
Chen H , Cretu C , Trebilcock A , Evdokimova N , Babai N, Feldmann L, Leidner F, Benseler F , Mutschall S , Esch K , Szabo CZK, Pena V , Pape C , Grubmuller H , Strenzke N , Brose N , Wichmann C , Preobraschenski J , Moser T
(2025) Sci Adv , 11 , eady8532 - eady8532
PUBMED: 41091875
DOI: doi:10.1126/sciadv.ady8532
ISSN: 2375-2548