EMD-52193

Single-particle
3.5 Å
EMD-52193
3D View Gallery
Deposition: 27/11/2024
Map released: 31/12/2025
Last modified: 04/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-52193
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9szt summary report (pdf.gz) Map and 9szt FULL report (pdf.gz)
EMICSS annotations (xml)

Co-chaperone Bag1-bound human 26S proteasome in SBAG2 state

EMD-52193

Single-particle
3.5 Å
EMD-52193
3D View Gallery
Deposition: 27/11/2024
Map released: 31/12/2025
Last modified: 04/03/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Co-chaperone Bag1-bound human 26S proteasome in SBAG2 state
Fitted models: 9szt

Deposition Authors: Cheng TC, Sakata E, Muntaner J, Maestro-Lopez M, Cuellar J, Valpuesta JM
Structures of the 26 S proteasome in complex with the Hsp70 co-chaperone Bag1 reveal a mechanism for direct substrate transfer.
Maestro-Lopez M, Cheng TC, Muntaner J, Menendez M, Alonso M, Schweitzer A, Ishizaka M, Tomko Jr RJ, Cuellar J, Valpuesta JM, Sakata E
(2026) Sci Adv , 12 , eadz3026 - eadz3026
PUBMED: 41719407
DOI: doi:10.1126/sciadv.adz3026
ISSN: 2375-2548