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EMD-52165
In vitro grown WT Alpha-Synuclein Fibrils
EMD-52165
Single-particle2.7 Å
Deposition: 20/11/2024Map released: 29/01/2025
Last modified: 08/10/2025
Sample Organism:
Homo sapiens
Sample: WT Alpha-Synuclein
Fitted models: 9hgr
Deposition Authors: Sicking K, Al-Azzani M, Outeiro TF, Fernandez-Busnadiego R
Sample: WT Alpha-Synuclein
Fitted models: 9hgr
Deposition Authors: Sicking K, Al-Azzani M, Outeiro TF, Fernandez-Busnadiego R
A novel alpha-synuclein G14R missense variant is associated with atypical neuropathological features.
Brucke C,
Al-Azzani M,
Ramalingam N,
Ramon M,
Sousa RL,
Buratti F
,
Zech M,
Sicking K,
Amaral L
,
Gelpi E,
Chandran A,
Agarwal A,
Chaves SR,
Fernandez CO,
Dettmer U,
Lautenschlager J,
Zweckstetter M,
Busnadiego RF,
Zimprich A,
Outeiro TF
(2025) Mol Neurodegener , 20 , 98 - 98
,
Zech M,
Sicking K,
Amaral L
,
Gelpi E,
Chandran A,
Agarwal A,
Chaves SR,
Fernandez CO,
Dettmer U,
Lautenschlager J,
Zweckstetter M,
Busnadiego RF,
Zimprich A,
Outeiro TF
(2025) Mol Neurodegener , 20 , 98 - 98
Grant Support:
- German Research Foundation (DFG): EXC 2067/1-390729940 (Germany)
- German Research Foundation (DFG): SFB1286 (B8) (Germany)
- German Research Foundation (DFG): SFB1286 (A12) (Germany)
- German Research Foundation (DFG): 448415290 (Germany)
- Michael J. Fox Foundation: ASAP-000282 (United States)
