Structure for benzamidine (S01.151 inhibitor)

Summary Structure Literature

PDB	Organism	Resolution	Comment
1A0J	Salmo salar	1.70 Å	complex with benzamidine inhibitor
The structural calcium ion is shown as yellow CPK sphere. Catalytic residues are shown in ball-and-stick representation: His55 in purple, Asp99 in pink and Ser192 in orange.

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1BIT	Salmo salar	1.83 Å	complex with benzamidine inhibitor
The structural calcium ion is shown as yellow CPK sphere. Catalytic residues are shown in ball-and-stick representation: His60 in purple, Asp104 in pink and Ser196 in orange.

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1BRA	Rattus norvegicus	2.20 Å	complex with benzamidine
Only the peptidase molecule is shown. Catalytic residues are shown in ball-and-stick representation: His63 in purple, Asp107 in pink and Ser200 in orange.

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1LO6_A	Homo sapiens	1.56 Å	complex with benzamidine inhibitor
Catalytic residues are shown in ball-and-stick representation: His62 in purple, Asp106 in pink and Ser197 in orange. Bound inhibitor benamidine is shown in grey.

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1RTF	Homo sapiens	2.30 Å	catalytic domain; complex with benzamidine
Catalytic residues are shown in ball-and-stick representation: His357 in purple, Asp406 in pink and Ser513 in orange.

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TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
trypsin 1 ( Bos taurus)
complex with benzamidine	1.40 Å	1C1N	1C1N	1C1N	1C1N	1C1N	1C1N	Katz et al., 1998
complex with benzamidine	1.43 Å	1C5P	1C5P	1C5P	1C5P	1C5P	1C5P	Katz et al., 2000
beta-trypsin; complex with benzamidine	1.90 Å	1CE5	1CE5	1CE5	1CE5	1CE5	1CE5	Ota et al., 1999
complex with benzamidine inhibitor	1.21 Å	1J8A	1J8A	1J8A	1J8A	1J8A	1J8A
complex with benzamidine	1.02 Å	1S0R	1S0R	1S0R	1S0R	1S0R	1S0R
complex with benzylamine	1.90 Å	2BZA	2BZA	2BZA	2BZA	2BZA	2BZA	Ota et al., 1999
complex with benzamidine containing polypeptide mediated crystal contacts	1.50 Å	2J9N	2J9N	2J9N	2J9N	2J9N	2J9N	Viola et al., 2007
complex with benzamidine at high temperature (35 c)	1.32 Å	2OXS	2OXS	2OXS	2OXS	2OXS	2OXS
beta-trypsin; complex with benzamidine	1.70 Å	3PTB	3PTB	3PTB	3PTB	3PTB	3PTB
trypsin-1 (fish) ( Gadus morhua)
complex with benzamidine	1.85 Å	2EEK	2EEK	2EEK	2EEK	2EEK	2EEK
thrombin ( Homo sapiens)
alpha-thrombin; complex with des-Asp55 hirudin and benzamidine	3.16 Å	1DWB	1DWB	1DWB	1DWB	1DWB	1DWB	Banner & Hadvary, 1991
urokinase-type plasminogen activator ( Homo sapiens)
complex with B-chain benzamidine inhibitor	1.80 Å	1F5K	1F5K	1F5K	1F5K	1F5K	1F5K	Zeslawska et al., 2000
kallikrein-related peptidase 6 ( Homo sapiens)
complex with benzamidine inhibitor	1.75 Å	1L2E	1L2E	1L2E	1L2E	1L2E	1L2E	Bernett et al., 2002
complex with benzamidine inhibitor	1.56 Å	1LO6	1LO6	1LO6	1LO6	1LO6	1LO6
t-plasminogen activator ( Homo sapiens)
catalytic domain; complex with benzamidine	2.30 Å	1RTF	1RTF	1RTF	1RTF	1RTF	1RTF	Lamba et al., 1996
coagulation factor XIa ( Homo sapiens)
catalytic domain Ser434Ala, Thr475Ala, Lys437 mutant; complex with benzamidine	1.96 Å	1ZHM	1ZHM	1ZHM	1ZHM	1ZHM	1ZHM	Jin et al., 2005
catalytic domain Ser434Ala, Thr475Ala, Lys505 mutant; complex with benzamidine	2.70 Å	1ZHP	1ZHP	1ZHP	1ZHP	1ZHP	1ZHP	Jin et al., 2005
catalytic domain Ser434Ala/Thr475Ala/Cys482Ser/Lys437Ala mutant; complex with benzamidine	1.73 Å	1ZHR	1ZHR	1ZHR	1ZHR	1ZHR	1ZHR	Jin et al., 2005
coagulation factor VIIa ( Homo sapiens)
complex with benzamidine and soluble tissue factor	1.87 Å	2AER	2AER	2AER	2AER	2AER	2AER	Bajaj et al., 2006
coagulation factor XIIa ( Homo sapiens)
complex with benzamidine	2.32 Å	6B74	6B74	6B74	6B74	6B74	6B74
trypsin 1 (Rattus-type) ( Rattus norvegicus)
complex with benzamidine	2.20 Å	1BRA	1BRA	1BRA	1BRA	1BRA	1BRA	Perona et al., 1993
trypsin-3 (fish) ( Salmo salar)
complex with benzamidine inhibitor	1.70 Å	1A0J	1A0J	1A0J	1A0J	1A0J	1A0J	Schroder et al., 1998
trypsin-1 (fish) ( Salmo salar)
complex with benzamidine inhibitor	1.83 Å	1BIT	1BIT	1BIT	1BIT	1BIT	1BIT	Berglund et al., 1995
complex with benzamidine	1.80 Å	1TBS	1TBS	1TBS	1TBS	1TBS	1TBS	Smalas et al., 1994
complex with benzamidine inhibitor	1.80 Å	2TBS	2TBS	2TBS	2TBS	2TBS	2TBS	Smalas et al., 1994