Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q9UI10

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-523	P	release of an initiating methionine	MS	Van Damme P et al., 2005
118	granzyme A	1-523	N			Van Damme et al., 2010
128	trypsin 1	1-523	N		MS	Schilling & Overall, 2008
142	trypsin 1	1-523	N		MS	Schilling & Overall, 2008