Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q9NVA2

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-429	P		NT	<%Agarwal et al., 2012[]%>
14	trypsin 1	2-429	N		MS	Schilling & Overall, 2008
19	cathepsin L	15-34	N		MS	Biniossek et al., 2011
34	trypsin 1	2-429	N		MS	Schilling & Overall, 2008
54	trypsin 1	2-429	N		MS	Schilling & Overall, 2008
65	trypsin 1	2-429	N		MS	Schilling & Overall, 2008
162	trypsin 1	2-429	N		MS	Schilling & Overall, 2008
170	trypsin 1	2-429	N		MS	Schilling & Overall, 2008
258	cathepsin L	254-272	N		MS	Biniossek et al., 2011
406	cathepsin L	400-418	N		MS	Biniossek et al., 2011