Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q9HB71

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-228	P		NT	<%Agarwal et al., 2012[]%>
8	meprin alpha subunit	2-228	N		MS	Becker-Pauly et al., 2011
8	meprin beta subunit	2-228	N		MS	Becker-Pauly et al., 2011
111	trypsin 1	2-228	N		MS	Schilling & Overall, 2008
118	trypsin 1	2-228	N		MS	Schilling & Overall, 2008
133	cathepsin L	124-143	N		MS	Biniossek et al., 2011
176	trypsin 1	2-228	N		MS	Schilling & Overall, 2008
184	meprin beta subunit	181-197	N		MS	Becker-Pauly et al., 2011
196	trypsin 1	2-228	N		MS	Schilling & Overall, 2008
207	lysyl endopeptidase (bacteria)	1-228	N		MS