Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q5SP16

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Click here to display alignment and conservation of cleavage sites of this sequence with close homologues. This will take a few moments.

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
55	trypsin 1	1-476	N		MS	Schilling & Overall, 2008
71	trypsin 1	1-476	N		MS	Schilling & Overall, 2008
81	trypsin 1	1-476	N		MS	Schilling & Overall, 2008
134	trypsin 1	1-476	N		MS	Schilling & Overall, 2008
136	trypsin 1	1-476	N		MS	Schilling & Overall, 2008
146	trypsin 1	1-476	N		MS	Schilling & Overall, 2008
163	trypsin 1	1-476	N		MS	Schilling & Overall, 2008
177	trypsin 1	1-476	N		MS	Schilling & Overall, 2008
196	trypsin 1	1-476	N		MS	Schilling & Overall, 2008
219	trypsin 1	1-476	N		MS	Schilling & Overall, 2008
359	trypsin 1	1-476	N		MS	Schilling & Overall, 2008
368	trypsin 1	1-476	N		MS	Schilling & Overall, 2008
370	trypsin 1	1-476	N		MS	Schilling & Overall, 2008
374	trypsin 1	1-476	N		MS	Schilling & Overall, 2008
385	trypsin 1	1-476	N		MS	Schilling & Overall, 2008
394	trypsin 1	1-476	N		MS	Schilling & Overall, 2008
432	trypsin 1	1-476	N		MS	Schilling & Overall, 2008
463	trypsin 1	1-476	N		MS	Schilling & Overall, 2008