Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q14141

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-434	P		NT	<%Agarwal et al., 2012[]%>
15	trypsin 1	2-434	N		MS	Schilling & Overall, 2008
21	cathepsin B	16-35	N		MS	Biniossek et al., 2011
35	trypsin 1	2-434	N		MS	Schilling & Overall, 2008
55	trypsin 1	2-434	N		MS	Schilling & Overall, 2008
66	trypsin 1	2-434	N		MS	Schilling & Overall, 2008
163	trypsin 1	2-434	N		MS	Schilling & Overall, 2008
171	trypsin 1	2-434	N		MS	Schilling & Overall, 2008
407	cathepsin L	401-420	N		MS	Biniossek et al., 2011