Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q04695

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-432	P		NT	<%Agarwal et al., 2012[]%>
241	caspase-6	2-432	P			Badock et al., 2001
257	meprin beta subunit	2-432	N		MS	Becker-Pauly et al., 2011
271	meprin beta subunit	2-432	N		MS	Becker-Pauly et al., 2011
272	meprin alpha subunit	2-432	N		MS	Becker-Pauly et al., 2011
272	meprin beta subunit	2-432	N		MS	Becker-Pauly et al., 2011
413	meprin alpha subunit	2-432	N		MS	Becker-Pauly et al., 2011
413	meprin beta subunit	2-432	N		MS	Becker-Pauly et al., 2011
417	caspase-7	2-432	P			Badock et al., 2001